MT2017-45 :CAR-T Cell Therapy for Heme Malignancies
Condition(s)
Leukemia Lymphoma
Leukemia Lymphoma
Age Group
0-9 years 10-17 years 18-26 years 27 years and older
0-9 years 10-17 years 18-26 years 27 years and older
Phase(s)
2
2
Drug
Fludarabine Cyclophosphamide
Biological
Kymriah Yescarta
Trial Summary & Details
Ages: Child, Adult, Older Adult
Condition: Acute Lymphoblastic Leukemia, Large B-cell Lymphoma
Condition: Acute Lymphoblastic Leukemia, Large B-cell Lymphoma
This is a phase II study of FDA-approved CAR-T products for patients with hematologic malignancies. Patients will be assigned to Arm A and B based on age and diagnosis. Overall remission rate, safety events and other endpoints will be calculated for Arm A and B separately.